Lazertinib
CAY-29670-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
1903008-80-9
Formulation
A solid
Purity
≥98%
MW
554,64308
Shipment
-20
Long Term Storage
-20
Shelf Life
730
Description
An irreversible inhibitor of mutant EGFRs (IC50s = 1.7, 2, and 3.3 nM for EGFRL858R/T790M, EGFRDel19/T790M, and EGFRDel19, respectively); selective for mutant EGFRs over wild-type EGFR, HER2, and HER4 (IC50s = 76, 364, and 1,017 nM, respectively); reduces viability of Ba/F3 cells expressing mutant EGFRs (IC50s = 3.3-5.7 nM); reduces tumor volume in an EGFRT790M mutant H1975 NSCLC mouse xenograft model at 1, 3, and 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
