LATS-IN-1
CAY-36623-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1424635-83-5
Formulation
A solid
Purity
≥98%
MW
334,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
LATS-IN-1 is an inhibitor of large tumor suppressor kinase 1 (LATS1) and LATS2 (IC50 = 2 nM for both), key regulators of Hippo regenerative signaling.{64599} It inhibits phosphorylation of YES1-associated transcriptional regulator (YAP1) in serum-starved HEK293A cells (EC50 = 510 nM). LATS-IN-1 (10 µM) increases the proliferation of Müller glial cells and isolated mouse cardiomyocytes.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
