Synonyms: 4-Isothioureidobutyronitrile|NSC 525990


CAS
66592-89-0
Formulation
A crystalline solid
Purity
≥95%
MW
179,67182
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An activator of p53; increases levels of activated p53 and expression of p21 in A549 cells and decreases expression of the transcription factor E2F1 in a variety of cell lines; decreases cell viability in a panel of cancer cell lines (mean IC50 = 0.49 μM); reduces tumor growth in various mouse xenograft models at 200 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).