KJ Pyr 9
CAY-19116-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
581073-80-5
Formulation
A crystalline solid
Purity
≥98%
MW
385,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
KJ Pyr 9 is a cell-permeable inhibitor of c-Myc (Kd = 6.5 nM) that interferes with Myc-Max complex formation in cells.{31163,31164} It preferentially blocks the proliferation of c-Myc-overexpressing cells, reducing Myc-driven gene expression.{31163} KJ Pyr 9 also potently blocks cell growth directed by overexpression of v-Myc, while less effectively blocking N-Myc- and L-Myc-dependent proliferation.{31164} It is effective in vivo, reducing the growth of breast cancer MDA-MB-231 xenografts in mice.{31163}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
