KCC009
CAY-42453-100 100 mg
Data Sheet: 
SDS:
SDS:
CAS
744198-19-4
Formulation
A solid
Purity
≥98%
MW
476,3206
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of TG2 (Ki = 0.068 mM); reduces radiation-induced increases in TGM2 expression in wild-type H1299 and H1299/M175H-p53 cells at 3.91 µM; sensitizes wild-type H1299 and H1299/M175H-p53 cells to radiation and induces cell cycle arrest at the G0/G1 and G2/M phases, respectively; inhibits fibronectin remodeling in U87MG glioblastoma cells at 1 mM; sensitizes tumors to N,N’-bis(2-chloroethyl)-N-nitrosourea and increases survival in an orthotopic mouse model of DBT-FG glioblastoma when administered in combination with N,N’-bis(2-chloroethyl)-N-nitrosourea at 50 mg/kg; reverses warfarin-induced arterial calcification in rats; prevents relapse in a rat model of EAE
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
