Synonyms: JNJ38158471
CAS
951151-97-6
Purity
>95%
MW
364.8
Shipment
AMBIENT
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 2 years after receipt when stored at -20°C.
Description
Chemical. CAS: 951151-97-6. Formula: C15H17ClN6O3. MW: 364.8. JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC(50) of 40nM. It also inhibits closely related tyrosine kinases such as Ret (IC(50) of 180nM) and Kit (C50 of 500nM). It has no significant activity (>1µM) against VEGFR-1 and VEGFR-3.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).