IQ-1S (free acid)
CAY-29851-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
23146-22-7
Formulation
A solid
Purity
≥98%
MW
247,25158
Shipment
-20
Long Term Storage
-20
Shelf Life
4 years from production
Description
An inhibitor of NF-κB/AP-1 (IC50 = 2.3 µM in a reporter assay); inhibits the production of TNF-α and IL-6 production in human Mono-Mac-6 cells (IC50s = 1.3 and 3.8 µM, respectively) and isolated human PBMCs (IC50s = 2.6 and 5.6 µM, respectively), as well as NO production in murine J774-A.1 macrophages (IC50 = 3.1 µM); binds to JNKs (Kd = 0.24, 0.36, and 0.1 for JNK1-3), as well as CK1δ, PI3Kγ, and MKNK2 (Kds = 0.38, 0.47, and 0.92 µM, respectively)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
