
CAS
1300031-49-5
Formulation
A crystalline solid
Purity
≥98%
MW
415,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An isoxazole class pan-BET family inhibitor, blocking BRD2, BRD3, and BRD4 with IC50 values of 0.5, 0.25, and 0.79 µM, respectively); induces apoptosis or triggers G0/G1 cell cycle arrest in MLL-fusion cell lines; effective in vivo, suppressing MLL leukemia progression in two different mouse models
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).