GLPG1690
CAY-25498-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1628260-79-6
Formulation
A crystalline solid
Purity
≥98%
MW
588,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
GLP1690 is a potent inhibitor of autotaxin (Ki = 15 nM).{36941} It inhibits the production of lysophosphatidic acid (LPA) in mouse, rat, and human plasma (IC50s = 418, 542, and 242 nM, respectively). GLPG1690 (30 mg/kg) reduces extracellular matrix deposition in the lung as well as LPA 18:2 levels in bronchoalveolar lavage fluid in a mouse model of pulmonary fibrosis induced by bleomycin (Item No. 13877).
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
