
Formulation
A lyophilized powder
Purity
≥95%
MW
2491,90806
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A peptide vasoconstrictor and agonist of ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively); induces contraction of pig coronary artery strips (EC50 = 0.52 nM), vasoconstriction of pig cardiac ventricular membrane (120% of control), and increases mean early pressor phase blood pressure by 66 mg Hg in rats when administered at a dose of 1 nmol/kg; stabilizes and induces nuclear translocation of HIF-1α and HIF-2α) via ETB in human lymphatic endothelial cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).