DCP-LA
CAY-21375-500 500 µg
Data Sheet: 
CAS
28399-31-7
Formulation
A solution in ethanol
Purity
≥95%
MW
308,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An activator of PKCε; activates PKCε with a >7-fold stronger potency over PKCα, βI, βII, γ, δ, μ, η, and ζ in a cell-free assay; activates PKC in PC12 cells in a concentration-dependent manner; decreases intracellular levels of Aβ in Neuro2 neuroblastoma cells transfected with human APPSwe/PS1Δ9; stimulates hippocampal glutamate release, striatal dopamine release, and hypothalamic serotonin release in rat brain slices in a PKC- and α7-containing nAChR- dependent manner; prevents synaptic loss and amyloid plaque formation and decreases escape latency in the Morris water maze in the 5XFAD transgenic mouse model of Alzheimer's disease at 3 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
