CAS
1872387-43-3
Formulation
A solid
Purity
≥95%
MW
552,58046
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A PPT1 inhibitor; binds to PPT1 and inhibits PPT1 enzyme activity in A375 cells at 5, 10, and 100 µM; inhibits autophagic flux and induces apoptosis in B-RAF mutant melanoma cell lines at 10 µM; induces STING activation and enhances antigen-primed T cell-mediated killing of B16/F10 murine melanoma cells in mouse splenocyte co-cultures; reduces intratumor autophagy and suppresses tumor growth in an HT-29 mouse xenograft model at 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).