D-α-Hydroxyglutaric Acid (sodium salt)
CAY-11605-250 250 mg
Synonyms: D-2-HG|D-2-Hydroxyglutaric Acid|DGA|R-2HG
Data Sheet: 
CAS
103404-90-6
Formulation
A crystalline solid
Purity
≥95%
MW
192,1
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An α-hydroxy acid; decreases the OCR and ratio of ATP to ADP in U87 cells at 800 µM; increases the levels of TBARS in isolated rat cerebral cortex homogenates at 100 µM; urinary levels are increased in D-2-hydroxyglutaric aciduria, a neurometabolic disease characterized by epilepsy, muscle hypotonia, and delays in psychomotor development; structurally similar to α-ketoglutarate and competitively inhibits α-ketoglutarate-dependent dioxygenases, including histone lysine demethylases and DNA hydroxylases
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
