Curcumin (high purity) Lipodisq Sterile Solution
IAX-700-101-L001 1 ml
Data Sheet: 
Purity
>95% (HPLC)
Shipment
Ambient
Short Term Storage
+4°C
Long Term Storage
+4°C
Shelf Life
Stable for at least 1 year after receipt when stored at +4°C.
Description
Chemical. CAS: 458-37-7. Formula: C21H20O6. MW: 368.4. Curcumin (high purity) Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Curcumin is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with anti-oxidant, anti-inflammatory, anti-cancer, anti-viral and anti-bacterial activities [1-20]. However, curcumin shows poor absorption, biodistribution, metabolism and bioavailability. To increase the bioavailability, enhance circulation, improve permeability and resistance to metabolic processing several formulations of curcumin have been prepared which include nanoparticles, liposomes, micelles and phospholipid complexes [21-25]. Curcumin (high purity) Lipodisq is based on a nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane molecules. The resulting encapsulated actives are rendered water-soluble and specialized for intra-cellular penetration/delivery via endosomal uptake mechanisms. Lipodisq solutions show a good safety profile and are suitable for in vitro and in vivo investigations.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
