Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate
CAY-10858-5 5 mg
CAS
132465-11-3
Formulation
A crystalline solid
Purity
≥97%
MW
321,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A 5-LO inhibitor (IC50 = 15 nM); selective for 5-LO over 12-LO and 15-LO (IC50s = 500 and 300 nM, respectively); inhibits A23187-induced 5-LO product formation in isolated human PMNs, monocytes, and whole blood (IC50s = 0.5, 0.45, and 1.5 µM, respectively); increases survival in a mouse model of PAF-induced lethal shock at 3.5 mg/kg; reduces pleural levels of LTB4 in a rat model of carrageenan-induced pleurisy
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
