CP 673,451
CAY-19170-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
343787-29-1
Formulation
A crystalline solid
Purity
≥98%
MW
417,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
CP-673,451 is a selective inhibitor of the platelet-derived growth factor receptor β (PDGFRβ) kinase with an IC50 value of 1 nM.{30922} It also inhibits the PDGFRα kinase (IC50 = 10 nM), but exhibits greater than 450-fold selectivity over other angiogenic receptors such as VEGFR 2, TIE-2, and FGR2.{30922} In several in vivo tumor models, CP-673,451 has antiangiogenic and antitumor activity.{30922,30923,30921}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
