CP 671,305
CAY-26743-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
445295-04-5
Formulation
A crystalline solid
Purity
≥98%
MW
454,404643
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent PDE4D inhibitor (IC50 = 3 nM); selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all); inhibits release of LTE4 from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM); inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
