CP 376,395
CAY-29188-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
175140-00-8
Formulation
A crystalline solid
Purity
≥98%
MW
326,47578
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A CRF1 antagonist (IC50 = 5.1 nM); inhibits adenylate cyclase activity stimulated by ovine CRF in rat cerebral cortex and at human CRF1 receptors; inhibits CRF-induced increases in the acoustic startle response in rats at 17.8 mg/kg; increases the percentage of open arm entries and time spent in the open arms of the elevated plus maze in mice at 1.5 and 3 nmol; reduces ethanol consumption in rats trained on an intermittent access schedule at 10 mg/kg; increases pulmonary ventilation in rats under normocapnic and hypercapnic conditions at 5 nmol/0.1 μl
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
