CMPD101
CAY-26808-5 5 mg
Data Sheet: 
CAS
865608-11-3
Formulation
A crystalline solid
Purity
≥98%
MW
466,458589
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GRK2 and GRK3 inhibitor (IC50s = 18 and 5.4 nM, respectively); selective for GRK2 and GRK3 over GRK1, GRK5, GRK6, and GRK7 (IC50s = 3,100, 2,300, >30,000, and 25,000 nM, respectively), as well as ROCK2 and PKCα (IC50s = 1,400 and 8,100 nM, respectively); induces cAMP accumulation in HEK293 cells expressing human β2-adrenergic receptors (EC50 = 10 µM); inhibits electrical field stimulation-, norepinephrine-, phenylephrine-, endothelin-1-, and U-46619-induced contractions in isolated human prostate strips at 50 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
