CDKI-73
CAY-41099-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1421693-22-2
Formulation
A solid
Purity
≥98%
MW
394,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
CDKI-73 is an inhibitor of Cdk9/cyclin T1, Cdk1/cyclin B, and Cdk2/cyclin A complexes (Kis = 4, 4, and 3 nM, respectively).{67816} It is selective for these complexes over the Cdk7/cyclin H complex (Ki = 91 nM). CDKI-73 is cytotoxic to HCT116 colorectal cancer cells (GI50 = In vivo, CDKI-73 (100 mg/kg every three days) decreases tumor volume in an HCT116 mouse xenograft model to a greater extent than the DNA-crosslinking agent cisplatin (Item No. 13119).
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
