CD74 (mouse):Fc (mouse) (rec.)
CHI-MF-110CD74-C100 100 ug
Synonyms: CLIP; DHLAG; HLADG
Data Sheet: 
Reactivity
Mouse
Source / Host
HEK 293 cells
Purity
>98% (SDS-PAGE)
Shipment
BI
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Description
Protein. The extracellular domain of mouse CD74 (aa 56-215) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: <5EU/mg protein (LAL test; Lonza). Lyophilized from 0.2µm-filtered solution in PBS. Purity: >98% (SDS-PAGE). CD74 is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. The cytoplasmic portion of CD74 can be released by intramembrane cleavage to activate NFkB. CD74 is upregulated in several cancers and is also expressed by non-immune cells during inflammation.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
