Formulation
A crystalline solid
Purity
≥95%
MW
842,07816
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A calcium-like peptide; binds to calmodulin (Kd = 88 µM); activates phosphodiesterase in the presence of calmodulin; acts as a calcium channel blocker; inhibits calcium influx through glutamate receptor channels in cultured rat neocortical neurons and inhibits excitatory cytotoxicity (IC50 = 52.48 µM) and apoptosis (IC50 = 44.78 µM); prevents increases in lung alveolar inflammatory cells after six hours in sensitized guinea pigs challenged with ovalbumin in an allergic asthma model (1 mg/kg)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).