CAS
70375-24-5 | 65147-04-8 (free base)
Purity
>98%
MW
627.7 . 36.5
Shipment
AMBIENT
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 1 year after receipt when stored at -20°C.
Description
Chemical. CAS: 70375-24-5 | 65147-04-8 (free base). Formula: C31H45N7O7 . HCl. MW: 627.7 . 36.5. Boc-Val-Pro-Arg-AMC is a sensitive fluorogenic peptide substrate for α-thrombin (Km = 21 μM, kcat = 109 s-1) and the α-thrombin-staphylocoagulase complex (Km = 25 μM, kcat = 89 s-1). It also serves as a substrate vor Kallikrein 5 and 8. Activity is quantified by the release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380nm and emits at 440-460nm when interacting with a target enzyme. This substrate has also been used for the rapid detection of MRSA (methicillin-resistant Staphylococcus aureus).
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).