Anti-ZNRF2 Antibody
ABI-24390 100 µL
Synonyms: E3 ubiquitin-protein ligase ZNRF2, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2, RING-type E3 ubiquitin transferase
Reactivity
Human
Applications
WB
Shipment
Blue Ice
Long Term Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy
Shelf Life
After date of receipt, stable for at least 1 year at -20°C.
Description
Our ZNRF2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human ZNRF2 and is antigen affinity purified. It is great for use in WB. - Protein ubiquitination has been implicated recently in neural development, plasticity, and degeneration. ZNRF1/nin283, is a protein with a unique, evolutionarily conserved C-terminal domain containing a juxtaposed zinc finger/RING finger combination. ZNRF2, is another novel member of the family of ZNRF E3 ubiquitin ligases. Both ZNRF1 and ZNRF2 have E3 ubiquitin ligase activity and are highly expressed in the nervous system, particularly during development. In neurons, ZNRF proteins are located in different compartments within the presynaptic terminal: ZNRF1 is associated with synaptic vesicle membranes, whereas ZNRF2 is present in presynaptic plasma membranes. Data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
