Anti-TFAM (Transcription Factor A, mitochondrial) Antibody

  ABI-2001-TFAMt 25 µL

Data Sheet:    

---

Human, Mouse, and Rat  

ELISA, WB  

N/A  

Blue Ice  

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy  

After date of receipt, stable for at least 1 year at -20°C.  

---

Description

 

Our Anti-TFAM (Transcription Factor A, mitochondrial) primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat TFAM (Transcription Factor A, mitochondrial) and is neat serum. It is great for use in WB. - Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia (Hayashi et al., 2008). More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice (Morimoto et al., 2012). -

 

---