Anti-Synphilin-1 (Sph1) Antibody
ABI-R-116-100 100 µL
Synonyms: Synphilin-1a protein; synuclein alpha interacting protein; Synphilin-1; Synphilin 1; SNCAIP
Reactivity
Human and Rat
Applications
IHC-Frozen
Shipment
25°C (ambient)
Long Term Storage
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial age
Shelf Life
12 months after date of receipt (unopened vial).
Description
Our Anti-Synphilin-1 (Sph1) rabbit polyclonal primary antibody detects human and rat Synphilin-1 (Sph1), and is whole serum. It is validated for use in IHC-Frozen. - Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
