Anti-Metabotropic Glutamate Receptor 7 (Ser862) Antibody
ABI-p1230-862 100 µL
Synonyms: FLJ40498 antibody, GLUR7 antibody, Glutamate receptor metabotropic 7 antibody, GPRC1G antibody, GRM7 antibody, GRM7_HUMAN antibody, Metabotropic glutamate receptor 7 antibody, MGLU7 antibody, mGluR7 antibody, OTTHUMP00000206961 antibody, OTTHUMP0000021467
Data Sheet: 
Reactivity
Mouse and Rat
Applications
ELISA, WB
Concentration
Lot Dependent
Shipment
Blue Ice
Long Term Storage
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Shelf Life
After date of receipt, stable for at least 1 year at -20°C.
Description
Our Anti-Metabotropic Glutamate Receptor 7 (Ser862) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat Metabotropic Glutamate Receptor 7 (Ser862) and is antigen affinity purified. It is great for use in WB. - Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse (Bhattacharya et al., 2004; Francesconi et al., 2004; Wilson and Nicoll, 2001). The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of Ser-862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1 (Suh et al., 2008). -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
