Anti-MECP2 Antibody (BSA and Azide free)
ABI-75-273-CF 100 µL
Synonyms: Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Data Sheet: 
Reactivity
Human, Mouse, and Rat
Applications
IHC, ELISA
Clone
N227/21
Concentration
1 mg/mL
Shipment
Shipped on ice packs
Long Term Storage
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Shelf Life
12 months from date of receipt
Description
Our carrier-free Anti-MECP2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N227/21. It detects human, mouse, and rat MECP2, and is purified by Protein A chromatography. It is great for use in DB, IHC. - MeCP2 (Methyl-CpG Binding Protein 2) is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair and is not influenced by sequences flanking the methyl-CpGs. MeCP2 has been shown to mediate transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A (Nan et al., 1998). Defects in MeCP2 are the cause of Rett syndrome (RTT) (Amir et al., 1999). RTT is an X-linked dominant disease; it is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
