Anti-MAP1LC3C Antibody
ABI-R-140-100 100 µL
Synonyms: Microtubule-associated proteins 1A/1B light chain 3C; Microtubule-associated protein 1 light chain 3 gamma; MAP1A/MAP1B LC3 C; MAP1A/1B light chain 3 C; MAP1 light chain 3-like protein 3; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like m
Reactivity
Human
Applications
ICC, IHC-Frozen, WB
Shipment
25°C (ambient)
Long Term Storage
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial age
Shelf Life
12 months after date of receipt (unopened vial).
Description
Our Anti-Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) rabbit polyclonal primary antibody detects human Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C), and is whole serum. It is validated for use in ICC, IHC-Frozen, WB. - FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: LC3-I: Cytoplasm. LC3-II: Intracytoplasmic membrane; lipid-anchor. LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. SIMILARITY: Belongs to the MAP1 LC3 family. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
