Anti-Chapsyn-110 MAGUK Antibody FL550 Conjugate
ABI-75-284-FL550 200 µL
Synonyms: Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Data Sheet: 
Reactivity
Chicken, Human, Mouse, and Rat
Applications
IHC, ICC
Clone
N18/28
Concentration
0.5 mg/mL
Shipment
Shipped on ice packs
Long Term Storage
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Shelf Life
12 months from date of receipt
Description
Our Anti-Chapsyn-110 MAGUK mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N18/28. It is KO validated, detects human, mouse, and rat Chapsyn-110 MAGUK, and is purified by Protein A chromatography. It is great for use in IHC, ICC. - PSD-93/Chapsyn-110 (also known as Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Disks large homolog 2 and Dlg2) is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains a guanylate kinase-like domain, 3 PDZ domains and 1 SH3 domain. Chapsyn110 binds to NMDA receptor subunits and Shaker K+ channel subunits to aid in forming a multiprotein scaffold which clusters receptors, ion channels, cytoskeletal protiens and other cell signaling proteins. In this manner, it plays a key role in postsynaptic targeting. It is found in brain in neuronal cells and located at the cell synapse, postsynaptic cell membrane and postsynaptic density. Chapsyn110 has been implicated in chronic pain, bilateral retinoblastoma and schizophrenia. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
