Anti-CLASP1 (C-terminus) Antibody
ABI-CM5011 100 µL
Synonyms: CLIP1, CLIP, Cytoplasmic linker, Kiaa0622; MAP1, POH1, MAST1, Microtubule
Data Sheet: 
Reactivity
Chicken, Human, Mouse, Rat, and Xenopus
Applications
ELISA, WB, ICC
Clone
KT66
Shipment
Blue Ice
Long Term Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy
Shelf Life
After date of receipt, stable for at least 1 year at -20°C.
Description
Our CLASP1 (C-terminus) primary antibody from PhosphoSolutions is rat monoclonal. It detects chicken, human, mouse, rat, and Xenopus CLASP1 (C-terminus) and is Protein G purified. It is great for use in WB, ICC. - The microtubule (MT) plus-end is a crucial site for the regulation of MT dynamics and interactions by several groups of plus-end tracking proteins (+TIPs). These +TIPs form comet-like accumulations at the plus ends of MTs to regulate MT dynamics and interactions with organelles and macromolecular complexes. The +TIPs include diverse groups of proteins, such as motor and nonmotor proteins, MT polymerases and depolymerases as well as various regulatory and adaptor proteins. The CLIP-associated protein (CLASP) family includes CLASP1 and CLASP2 proteins, which are expressed as long (α) and short (β) isoforms. Thse +TIPs conatin an N-terminal TOG domain, multiple TOG-like domains, and a basic and serine-rich motif (SxIP). The TOG domain facilitates interaction with tubulin dimers, while the SxIP motif promotes interaciton with EB1 and MTs. A C-terminal domain is involved in interaction with CLIPs, as well as several other proteins. CLASPs are MT stabilizing fators that localize to mitotic spindles, kinetochores, and the midbody. CLASPs are important for cell division, and may regulate cell migration and neuronal growth cone motility. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
