Synonyms: COL25A1, Collagen alpha-1 XXV chain, Alzheimer disease amyloid-associated protein, AMY, Collagen-like Alzheimer amyloid plaque component
Reactivity
Human and Mouse
Applications
WB
Shipment
Blue Ice
Long Term Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy
Shelf Life
After date of receipt, stable for at least 1 year at -20°C.
Description
Our CLAC-P (NC2-2 region) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and mouse CLAC-P (NC2-2 region) and is antigen affinity purified. It is great for use in WB. - Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).