Adomeglivant
CAY-29668-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1488363-78-5
Formulation
A solid
Purity
≥98%
MW
555,627789
Shipment
-20
Long Term Storage
-20
Shelf Life
4 years from production
Description
An allosteric antagonist of the glucagon receptor; inhibits glucagon-induced increases in cAMP levels in HEK293 cells expressing the rat glucagon or GLP-1 receptors (IC50s = 1.8 and 1.2 µM, respectively) but has no effect on cAMP levels when used alone; inhibits increases in cAMP levels induced by GLP-1 or exendin-4 in HEK293 cells expressing the GLP-1 receptor (IC50s = 7 and 12 µM, respectively); decreases glucose-stimulated insulin secretion at 1 µM in combination with exendin (9-39) in isolated human islets but not glucose-stimulated glucagon secretion alone or in combination with exendin (9-39) in isolated mouse islets
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
