CAS
2035509-96-5
Formulation
A solid
Purity
≥98%
MW
648,77692
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An ERK5 inhibitor (IC50 = 8 nM); selective for ERK5 over a panel of 100 other kinases at 1 µM; inhibits ERK5 autophosphorylation in HeLa cells at 1 µM; induces apoptosis in combination with ivermectin in A375 spheroids at 1 µM; decreases skin thickness and scaling in a mouse model of imiquimod-induced allergic skin inflammation at 15 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).