ARM1
CAY-15865-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
68729-05-5
Formulation
A crystalline solid
Purity
≥95%
MW
268,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Item No. 20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro.{12673,20329} ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 µM).{25663} ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.{25663}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
