AR-V7 Antibody / Androgen Receptor
NSJ-V5456-100UG 100 ug
Data Sheet: 
Reactivity
Human
Applications
IHC-P
Source / Host
Rabbit
Immunogen
A recombinant fragment (within amino acids 600-920) of human AR protein (AR-V7 specific) was used as the immunogen for the recombinant Androgen Receptor V7 antibody.
Clone
DHTR.V7/9125R
Purity
Protein A/G affinity
Long Term Storage
Aliquot the recombinant Androgen Receptor V7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Description
AR V7 belongs to the nuclear hormone receptor family. It contains the nuclear receptor DNA binding domain. Steroid hormone receptors are ligand-activated transcription factors that regulate the expression of eukaryotic genes affecting cell proliferation and differentiation in target tissues. The activity of transcription factors is regulated by binding co-activators and co-repressors. This target is a splice variant of the androgen receptor that lacks the C-terminal androgen-binding site. AR-V7 plays an important role in the occurrence, development and drug resistance of prostate cancer.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
