Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

5-Aza-2'-deoxycytidine (Decitabine)

  V13-14100 50 mg

 
Synonyms: DNA methylation, inhibitor, DNMT, 5-aza, methylation
 
Active Motif
5-Aza-2'-deoxycytidine (Decitabine)

Data Sheet:    

Shipment
Room Temp  

Short Term Storage
-20C  

Long Term Storage
Store desiccated as supplied at 4°C for up to 2 years. Store solutions at -20°C for up to 3 months.  


Description
 
Active Motif's 5-Aza-2'-deoxycytidine (Decitabine) inhibits DNA methyltransferases (DNMT). It induces demethylation and reactivation of silenced genes suppressing the growth of human tumor cell lines. It also increases stem cell reprogramming efficiency and stimulates osteogenic differentiation of human bone marrow stromal cells. 5-Aza-2'-deoxycytidine induces differentiation and growth inhibition in IDH1 mutant glioma cells and decreases tumor growth in vivo. It is cell permeable.
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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