Synonyms: covid, covid-19, covid19, coronavirus, Severe acute respiratory Coronavirus main protease kit, Mpro kit, 3-CL kit, 3C like protease assay
Applications
Great for studying enzyme kinetics and HTS applications.
Shipment
-80°C (dry ice)
Literature References
1. Morse, J.S., et al., 2020 Chem.Bio.Chem. 21: 730 - 738.
2. Chi-Pang, C., et al., 2011 PLoS ONE 6(11): e27228.
2. Chi-Pang, C., et al., 2011 PLoS ONE 6(11): e27228.
Description
The 3CL Protease Assay Kit is designed to measure 3CL Protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps. 3CL inhibitor GC376 is also included as an inhibitor control.
Coronaviruses (CoVs) primarily cause multiple respiratory and intestinal infections in humans and animals. Severe acute respiratory syndrome (SARS) is a highly contagious and often fatal viral respiratory illness caused by a coronavirus called SARS-CoV. It is highly homologous to SARS-CoV-2, the causative agent for COVID-19. The 3CL protease, also known as Main Protease (Mpro), plays a vital role in processing the polyproteins that are translated from the viral RNA. 3CL Protease inhibitors that can block viral replication are promising potential drug candidates that could be used to treat patients suffering with the coronavirus infection.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).