CAS
120964-45-6
Formulation
A crystalline solid
Purity
≥98%
MW
298,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An analog of 3-deazaadenosine, an inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in primary human AML cells in a dose-dependent manner (0.2-1 μM); acts synergistically with the pan-HDAC inhibitor panobinostat in inducing apoptosis of AML cells implanted in mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).