2'-Deoxy-5-fluorocytidine
V13-14109 50 mg
Synonyms: DNMT, DNA methylation, inhibitor, 5-aza, 5-azacytidine, methylation, decitabine
Data Sheet: 
Shipment
Room Temp
Short Term Storage
-20C
Long Term Storage
Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month.
Description
Active Motif's 2'-Deoxy-5-fluorocytidine is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5-Azacytidine and decitabine, 2'-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT-116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
