1-O-Acetylbritannilactone
CAY-35137-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
33627-41-7
Formulation
A solid
Purity
≥98%
MW
308,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
1-O-Acetylbritannilactone is a sesquiterpene lactone that has been found in I. britannica and has diverse biological activities.{60843,60844} It inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) and nuclear translocation of NF-κB in primary rat aorta vascular smooth muscle cells (VSMCs).{60843} 1-O-Acetylbritannilactone (5 and 10 µM) inhibits VEGF-induced capillary tube formation in human umbilical vein endothelial cells (HUVECs).{60844} It reduces tumor growth in an A549 mouse xenograft model when administered at a dose of 12 mg/kg per day.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
