CAS
300576-59-4
Formulation
A crystalline solid
Purity
≥98%
MW
285,8
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
(+)-PD 128907 is a potent agonist of the dopamine 3 (D3) receptor (Ki = 1 nM).{33953,33956} It shows selectivity for D3 over D2 and D4 receptors (Kis = 1.2 and 7 µM, respectively).{33953} Low doses of (+)-PD 128907 (13 µg/kg, s.c.) reduce spontaneous locomotor activity in rats.{33954} It blocks stereotypy induced by the NMDA receptor antagonist (+)-MK-801 (Item No. 10009019) in mice.{33957} (+)-PD 128907 is used in animal models to study the role of the D3 receptor in nervous system disorders, such as schizophrenia, Parkinson’s disease, and depression.{31907,33955}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).