(−)-Borneol
CAY-23468-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
464-45-9
Formulation
A crystalline solid
Purity
≥95%
MW
154,3
Shipment
-20
Long Term Storage
-20
Shelf Life
48 months
Description
(−)-Borneol is a bicyclic monoterpene originally found in A. canadense.{36773,36774} It is a positive allosteric modulator of α1β2γ2L subunit-containing GABAA receptors with an EC50 value of 237 µM for human recombinant receptors expressed in X. laevis oocytes.{36773} It increases the latency to first pentylenetetrazole- and maximal electroshock-induced seizure in mice when administered at doses of 50, 100, and 200 mg/kg.{36775} (–)-Borneol (300 mg/kg) also increases the permeability of the blood-brain barrier and increases the concentration of cisplatin reaching tumors in a mouse model of glioblastoma multiforme.{36776} Formulations containing (–)-borneol have been used as fragrance ingredients.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
