
CAS
64072-89-5
Formulation
A solution in methyl acetate
Purity
≥98%
MW
352,5
Shipment
-80
Long Term Storage
-80
Shelf Life
730
Description
PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. .DELTA.12-PGD2 is one of the initial chemical decomposition products of PGD2. .DELTA.12-PGD2 is an intermediate in the pathway leading to .DELTA.12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities.{870,334} The metabolism of .DELTA.12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.{7193}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).