Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy
vb@vincibiochem.it
Tel:+39 0571 568 147 -
 0571 568 135
Fax:+39 0571 568132 - P. IVA 05706610481

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Epigenetics & Chromatin


The field of epigenetics involves the study of chromatin-based phenomena and heritable changes in gene expression not resulting from changes in gene structure or sequence. DNA is wrapped around an octamer of histone proteins to form chromatin, then packaged into chromosomes by other structural proteins. The organization of genetic material in the nucleus has profound effects on all processes that require access to DNA. Much of the regulation of the genome involves histone modifications (e.g. acetylation, methylation, phosphorylation) and DNA methylation at CpG islands that regulated a myriad of signals that are critical to cell function.   

 

MotifVations Cancer Epigenetics
MotifVations April 2017
Cancer Epigenetics
Active Motif Scarica PDF
The Complicated Picture of Epigenetics in Cancer
NEW: High Quality ChIP-Seq Data from as Few as 1,000 Cells | NEW: NGS DNA Library Preparation with Molecular Identifiers Eliminates Bias from PCR Duplicates | NEW: Is DNA Methylation a Biomarker in Your FFPE Sample? | Obtain Whole-Genome Profiles from Clinical Samples with ChIP IT® FFPE? | NEW: Epigenomic Profiling of Tumors | NEW: AbFlex™ Recombinant Antibodies | NEW: A Genome-wide 3’UTR Collection for High-Throughput Functional Screening of miRNA Targets | ChIP Normalization Reagents Reduce Effects of Technical Variation and Reveal Subtle Biological Changes ! NEW: Assay-Ready Recombinant Proteins, Substrates, & Inhibitors
The ChIP Assay Expert Active Motif
The ChIP Assay Experts™
Active Motif
ChIP & Specialty ChIP Kits
Antibodies
Accessories
Sonicator
       
Cayman_Currents_27_Epigenetics
Cayman Currents Epigenetics
Bromodomain Targeting with Proteolysis Targeting Chimeras (PROTACs)
Medicinal Chemistry Services
Inhibitors: Writers, Erasers, and Readers
Researcher Spotlight: Peter J. Brown, Ph.D. SGC, University of Toronto
Assay Kits: Readers, Writers, and Erasers
Antibodies: Histones and Histone Modifications, DNA/RNA, and Other PTM Modifiers
Proteins: Readers, Writers, and Erasers
Proteins for Epigenetics
Recombinant Proteins for Epigenetic Research 
       
Active Motif MotifVations Neuroepigenetics Edition
Active Motif MotifVations Neuroepigenetics Edition
Epigenetic Modulation in Brain Disorders; High Quality ChlP-Seq Data from as Few as 5,000 Cells: NGS ONA Library Preparation with Molecular Identifiers; Easily Isolate Intact Histones for PTM Analysis; Is DNA Methylation a Biomarker in Your FFPE Sample? Simple High-throughput Screen to Evaluate Changes in Global DNA Methylation; Sortase 2.0 —A versatile proprietary protein labeling technology and kit; A Genome-wide 3'UTR Collection for High-throughput Functional Screening of miRNA Targets; Services: RRBS for Genome-scale DNA Methylation Profiling, FFPE ChIP-Seq 
Epigenetics Drug Discovery
Active Motif Epigenetic Drug Discovery
TOOLS FOR EPIGENETIC DRUG DISCOVERY 
Proteins
Nucleosomes
Antibodies
Assays
Services 
       
Protein-DNA Interactions Active Motif
Reagents and Kits for Analysis of Protein-DNA Interactions
Active Motif Sonication
Active Motif Sonication
 
products for SONICATION 
Probe Sonicators / Multi-sample Processors / Cooled Sonication Platform / Accessories 
       
Epigenetics Active Motif

Epigenetics -  Product and Services Active Motif

 

ChIP, Histones, DNA Methylation, Sample Preparation, Antibodies, Services

 

Scarica PDF

ChIP without specific antibodies
ChIP Normalization - Reduce the effects of technical variation
       
Cayman Inhibitors for Epigenetic Research
NEW Inhibitors for Epigenetic Research
 
More than 160 inhibitors available for epigenetic research
Epigenetics Screening Library (96-Well)
SAM Screener Assay Kits
SAM-Screener™ Assay Kits
Screen for SAM (S-adenosyl-L-methionine) competitive methyltransferase inhibitors with SAM-Screener™ one-step, fluorescence polarization assays.
Assay kits available for the following enzymes:
° SET7/9 (Item No. 600490)
° GLP (Item No. 600570)
° MLL1 (Item No. 600580)
       

Cayman Epigenetic Proteins and Antibodies

Epigenetic Proteins and Antibodies
Proteins for Epigenetic Research: PAD2 (human recombinant); More than 115 proteins available for epigenetic research
Antibodies for Epigenetic Research: Histone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody; More than 50 antibodies available for epigenetic research
Cayman Assay Kits for Epigenetic Research
Assay Kits for Epigenetic Research
 
More than 35 assay kits available for epigenetic research
EpiTitanTM Histone Peptide Array
       
Cayman Epigenetics Research Tools
Epigenetic Research Tools - Cayman 
 
Micro RNA selected publications
MicroRNA selected publications
       
Tools for Disease Research Active Motif
Tools for Disease Research
Targeting Epigenetics & Gene Regulation
Oncology
Inflammation
Immunology
Neuroscience
Neuroepigenetics Research Literature
Neuroepigenetics selected publications
       
Active Motif TransAM® Transcription Factor ELISAs
TransAM® Transcription Factor Assays are DNA-binding ELISAs that facilitate the study of transcription factor activation in mammalian tissue and cell extracts. With assays available for over 40 different targets and over 800 papers citing their use, TransAM Kits have become the method of choice for detecting and quantifying activated transcription factors.
Antibodies Active Motif Antibodies - Active Motif®
DNA Methylation
Chromatin
Histones
Cancer
Stem Cells
Transcription Factors
       
BPS HMT HDM flyer Histone Methylation BPS
Histone Methylation Assay Kits
Histone Methyltransferases
Histone Demethylases
DNA Demethylases
Cofactors/Related Proteins
Substrates
Histone Demethylase Inhibitor
HMT Inhibitors

Active Motif LightSwitch™ Luciferase  Assay System
The LightSwitch™ Luciferase Assay System includes over 18,000 promoters that have been cloned from the human genome into transfection-ready LightSwitch reporter vectors, which are assayed in living cells using our optimized luciferase assay reagents and protocols. Also available are Synthetic Response Element constructs and Pathway Reporter Stable Cell Lines. Scarica PDF
       

 



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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    Fax:+39 0571 568132
    P. IVA 05706610481