Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy
vb@vincibiochem.it
Tel:+39 0571 568 147 -
 0571 568 135
Fax:+39 0571 568132 - P. IVA 05706610481

Active Motif 

  

Vinci-Biochem Srl is the EXCLUSIVE DISTRIBUTOR FOR ITALY of Active Motif that develops innovative cell biology-based research tools and biocomputing resources, helping researchers to elucidate the function, regulation and interactions of the genes and their encoded proteins. Their goal is to provide customers with high-quality products complemented by superior service & support.

 

   

New Products for Epigenetics Research

 

  • FFPE Bisulfite Conversion Kit

    The FFPE Bisulfite Conversion Kit is designed for the analysis of DNA methylation profiles in FFPE tissue sections. It offers the advantage of providing optimized reagents throughout the workflow to improve recovery of high quality DNA, minimize degradation and provide greater than 99% conversion efficiency. More >

  • enChIP Kit to Confirm CRISPR/Cas9 Specificity

    The enChIP Kit uses the CRISPR/Cas9 system to direct a guide RNA (gRNA) and AM-tagged dCas9 protein to a specific genomic locus for immunoprecipitation. enChIP can be used to identify off-target binding effects. More >

  • Quantify Global Changes in 5-hmC

    The Global 5-hmC Quantification Kit is an ELISA-based assay designed to screen for differences in global 5-hydroxymethylcytosine (5-hmC) levels across samples or treatment conditions. The included DNA standards provide quantitative results that are consistent with mass spectrometry. More >

  • Specific Isolation of Nuclear and Cytoplasmic RNA

    The RNA Subcellular Isolation Kit makes it easier to study low abundance RNA transcripts and to demonstrate the role of lncRNA localization with RNA function by providing an efficient method to isolate nuclear or cytoplasmic RNA fractions without cross-contamination. More >

  • Perform ChIP Without Protein-specific Antibodies

    The Tag-ChIP-IT® Kit makes it easy to perform ChIP with transcription factor sequence variants, mutations or truncations by eliminating the need for protein-specific antibodies. Simply clone your protein sequence with Active Motif's unique AM-tag, specifically designed for use in ChIP, transfect your cells and perform ChIP using an antibody directed against the AM-tag. More >

  • Promoter Reporters Validated Using Pathway-specific Inductions

    The LightSwitch™ Validated Pathway Collections contain promoter reporter constructs that were experimentally validated to show significant activation or repression in response to pathway-specific induction conditions, so they are ideal for studying the key promoters that regulate a variety of different pathways, such as inflammation, hypoxia, DNA damage, heat shock, etc. More >

  • Reduce the Effects of Technical Variation In Your ChIP

    Active Motif has developed a ChIP Normalization Strategy that can be used to normalize ChIP qPCR and ChIP-Seq data to reduce the effects of technical variation and sample processing bias. This normalization strategy can be applied across samples and antibodies. More >

  • RIME Service: Identify Protein Interactions by Mass Spectrometry

    Adding to our growing list of Epigenetic Services offerings, Active Motif now offers RIME (Rapid Immunoprecipitation Mass spectrometry of Endogenous proteins), which allows for the identification of transcriptional co-factors and chromatin associated proteins. More >

  • Low Cell Number ChIP-Sequencing Services

    New advancements in our ChIP-Seq protocols and pipeline have reduced ChIP-Seq starting material requirements by 1,000 fold! In large contrast to the 10,000,000 cell requirement needed to perform standard ChIP-Seq, Active Motif now offers low cell number ChIP-Seq services, that allow you to perform ChIP-Seq with as few as 10,000 cells. More >

  • New Recombinant Nucleosomes for use in Enzymatic Assays and Chromatin Assembly

    Active Motif's Recombinant Nucleosomes offer a more biologically relevant choice of substrate when compared to histone proteins alone or synthetic peptides for use in drug discovery screening, analyzing enzyme kinetics or monitoring changes in histone modifications. Each recombinant nucleosome is comprised of octamers of unmodified core histone proteins (H2A, H2B, H3 and H4) bound by DNA. Biotin-tagged Nucleosomes are also available for pull-down or binding assays. More >

of the regulation of the genome involves histone modifications (e.g. acetylation, methylation, phosphorylation) and DNA methylation at CpG islands that regulated a myriad of signals that are critical to cell function.   

 

MotifVations Cancer Epigenetics
MotifVations April 2017
Cancer Epigenetics
Active Motif Scarica PDF
The Complicated Picture of Epigenetics in Cancer
NEW: High Quality ChIP-Seq Data from as Few as 1,000 Cells | NEW: NGS DNA Library Preparation with Molecular Identifiers Eliminates Bias from PCR Duplicates | NEW: Is DNA Methylation a Biomarker in Your FFPE Sample? | Obtain Whole-Genome Profiles from Clinical Samples with ChIP IT® FFPE? | NEW: Epigenomic Profiling of Tumors | NEW: AbFlex™ Recombinant Antibodies | NEW: A Genome-wide 3’UTR Collection for High-Throughput Functional Screening of miRNA Targets | ChIP Normalization Reagents Reduce Effects of Technical Variation and Reveal Subtle Biological Changes ! NEW: Assay-Ready Recombinant Proteins, Substrates, & Inhibitors
The ChIP Assay Expert Active Motif
The ChIP Assay Experts™
Active Motif
ChIP & Specialty ChIP Kits
Antibodies
Accessories
Sonicator
       
Epigenetics Drug Discovery
Active Motif Epigenetic Drug Discovery
TOOLS FOR EPIGENETIC DRUG DISCOVERY 
Proteins
Nucleosomes
Antibodies
Assays
Services 
Active Motif MotifVations Neuroepigenetics Edition
Active Motif MotifVations Neuroepigenetics Edition
Epigenetic Modulation in Brain Disorders; High Quality ChlP-Seq Data from as Few as 5,000 Cells: NGS ONA Library Preparation with Molecular Identifiers; Easily Isolate Intact Histones for PTM Analysis; Is DNA Methylation a Biomarker in Your FFPE Sample? Simple High-throughput Screen to Evaluate Changes in Global DNA Methylation; Sortase 2.0 —A versatile proprietary protein labeling technology and kit; A Genome-wide 3'UTR Collection for High-throughput Functional Screening of miRNA Targets; Services: RRBS for Genome-scale DNA Methylation Profiling, FFPE ChIP-Seq 
       
Epigenetics Active Motif

Epigenetics -  Product and Services Active Motif

ChIP, Histones, DNA Methylation, Sample Preparation, Antibodies, Services

Scarica PDF

ChIP Normalization Reagents
ChIP Normalization - Reduce the effects of technical variation
       
Micro RNA selected publications
MicroRNA selected publications
Active Motif
Protein-DNA Interactions Active Motif
Reagents and Kits for Analysis of Protein-DNA Interactions
       
Active Motif Sonication
Active Motif Sonication
 
products for SONICATION 
Probe Sonicators / Multi-sample Processors / Cooled Sonication Platform / Accessories 
Tools for Disease Research Active Motif
TOOLS FOR DISEASE RESEARCH
Targeting Epigenetics & Gene Regulation
Oncology
Inflammation
Immunology
Neuroscience
       
Proteins for Epigenetics Recombinant Proteins for Epigenetic Research 

Scarica PDF

Antibodies Active Motif Antibodies - Active Motif®
DNA Methylation
Chromatin
Histones
Cancer
Stem Cells
Transcription Factors
       
Active Motif TransAM® Transcription Factor ELISAs
TransAM® Transcription Factor Assays are DNA-binding ELISAs that facilitate the study of transcription factor activation in mammalian tissue and cell extracts. With assays available for over 40 different targets and over 800 papers citing their use, TransAM Kits have become the method of choice for detecting and quantifying activated transcription factors.
Neuroepigenetics Research Literature
Neuroepigenetics selected publications
       
       
       
 

 



ProductCodeSizePrice € Preventivo / Ordina
293 NUCLEAR EXTRACT
V13-36033 200 µg inquire  
2'-DEOXY-5-FLUOROCYTIDINE
V13-14108 250 mg inquire  
2'-DEOXY-5-FLUOROCYTIDINE
V13-14109 50 mg inquire  
3-METHYLCYTOSINE (3-MC) ANTIBODY (PAB)
V13-61111 100 µg inquire  
3-METHYLCYTOSINE (3-MC) ANTIBODY (PAB)
V13-61179 100 µl inquire  
3-METHYLCYTOSINE (3-MC) ANTIBODY (PAB), SAMPLE
V13-61112 10 µg inquire  
3-METHYLCYTOSINE (3-MC) ANTIBODY (PAB), SAMPLE
V13-61180 10 µl inquire  
3T3-L1 NUCLEAR EXTRACT
V13-36071 200 µg inquire  
5-AZA-2’-DEOXYCYTIDINE (DECITABINE)
V13-14100 50 mg inquire  
5-AZA-2’-DEOXYCYTIDINE (DECITABINE)
V13-14101 10 mg inquire  
5-AZACYTIDINE
V13-14102 250 mg inquire  
5-AZACYTIDINE
V13-14103 50 mg inquire  
5-CARBOXYLCYTOSINE (5-CAC) ANTIBODY (PAB)
V13-61225 100 µl inquire  
5-CARBOXYLCYTOSINE (5-CAC) ANTIBODY (PAB)
V13-61229 100 µg inquire  
5-CARBOXYLCYTOSINE (5-CAC) ANTIBODY (PAB), SAMPLE
V13-61226 10 µl inquire  
5-CARBOXYLCYTOSINE (5-CAC) ANTIBODY (PAB), SAMPLE
V13-61230 10 µg inquire  
5-CARBOXYLCYTOSINE DNA STANDARD
V13-55014 0.5 µg inquire  
5-FORMYLCYTOSINE (5-FC) ANTIBODY (PAB)
V13-61223 100 µl inquire  
5-FORMYLCYTOSINE (5-FC) ANTIBODY (PAB)
V13-61227 100 µg inquire  
5-FORMYLCYTOSINE (5-FC) ANTIBODY (PAB), SAMPLE
V13-61224 10 µl inquire  
5-FORMYLCYTOSINE (5-FC) ANTIBODY (PAB), SAMPLE
V13-61228 10 µg inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (MAB)
V13-39999 100 µg inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (MAB), SAMPLE
V13-40000 10 µg inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (PAB)
V13-39769 100 µl inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (PAB)
V13-39791 100 µg inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (PAB), SAMPLE
V13-39770 10 µl inquire  
5-HYDROXYMETHYLCYTOSINE (5-HMC) ANTIBODY (PAB), SAMPLE
V13-39792 10 µg inquire  
5-METHYLCYTOSINE (5-MC) ANTIBODY (MAB)
V13-39649 50 µg inquire  
5-METHYLCYTOSINE (5-MC) ANTIBODY (MAB)
V13-61479 100 µg inquire  
5-METHYLCYTOSINE (5-MC) ANTIBODY (MAB), SAMPLE
V13-61480 10 µg inquire  
5-METHYLCYTOSINE (5-MC) ANTIBODY (PAB)
V13-61255 100 µl inquire  
5-METHYLCYTOSINE (5-MC) ANTIBODY (PAB), SAMPLE
V13-61256 10 µl inquire  
6-THIOGUANINE
V13-14126 1 g inquire  
6-THIOGUANINE
V13-14127 100 mg inquire  
A20 ANTIBODY (MAB)
V13-40901 100 µg inquire  
A-431 NUCLEAR EXTRACT
V13-36004 200 µg inquire  
A-431 NUCLEAR EXTRACT (EGF TREATED)
V13-36003 200 µg inquire  
AARE SYNTHRE
V13-32101 5 µg inquire  
RECOMBINANT ABL1 PROTEIN
V13-31160 10 µg inquire  
RECOMBINANT ACF COMPLEX
V13-31509 20 µg inquire  
ACF1 ANTIBODY (PAB)
V13-39721 100 µl inquire  
ACF1 ANTIBODY (PAB), SAMPLE
V13-39722 10 µl inquire  
ACTL6B ANTIBODY (PAB)
V13-61691 100 µl inquire  
ACTL6B ANTIBODY (PAB), SAMPLE
V13-61692 10 µl inquire  
AEBP2 ANTIBODY (PAB)
V13-61539 100 µl inquire  
AEBP2 ANTIBODY (PAB), SAMPLE
V13-61540 10 µl inquire  
AFP1 SYNTHRE
V13-32102 5 µg inquire  
AGO1 ANTIBODY (MAB)
V13-61071 100 µg inquire  
AGO1 ANTIBODY (MAB), SAMPLE
V13-61072 10 µg inquire  
AGO1/2/3 ANTIBODY (MAB)
V13-39937 100 µg inquire  
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    Fax:+39 0571 568132
    P. IVA 05706610481