anti-5-Formylcytosines (5-fC), Rabbit Monoclonal (RM477)
REV-31-1369-00-C050 50 µg
Synonyms: 5-fC
Data Sheet: 
Reactivity
All
Applications
ELISA, DotBlot
Source / Host
Rabbit
Specificity
RM477 reacts to 5-Formylcytosine (5-fC) in DNA. No cross-reactivity with non-modified cytosine and other modified cytosines in DNA.
Clone
RM477
Purity
Protein A purified.
Shipment
BLUE ICE
Long Term Storage
-20°C
Shelf Life
Stable for at least 1 year after receipt when stored at -20°C.
Description
Recombinant Antibody. RM477 reacts to 5-Formylcytosine (5-fC) in DNA. No cross-reactivity with non-modified cytosine and other modified cytosines in DNA. Isotype: Rabbit IgG. Immunogen: KLH-conjugated 5-Formylcytosine. Applications: ELISA, DotBlot. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. 5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate 5-formylcytosine (5-fC) and 5-carboxylcytosine. It is believed that this conversion process may represent a pathway of DNA demethylation.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
