Synonyms: Sodium glycochenodeoxycholate; GCDCA; NSC 681056; Chenylglycine sodium; N-(3alpha,7alpha-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt


Source / Host
Synthetic.
CAS
16564-43-5
Purity
>97% (HPLC)
MW
471.61
Shipment
AMBIENT
Short Term Storage
+4°C
Long Term Storage
+20°C
Shelf Life
Stable for at least 2 years after receipt when stored at -20°C.
Description
Chemical. CAS: 16564-43-5. Formula: C26H42NNaO5. MW: 471.61. Synthetic. Glycochenodeoxycholic acid (GCDCA) is a bile salt formed in the liver that acts as a biosurfactant to solubilize lipids for absorption and is itself absorbed. GCDCA functions as a choleretic, increasing the volume of bile secreted from the liver, and a cholagogue, promoting the discharge of bile from the digestive system. GCDCA has been used to demonstrate a role for bile acids in promoting colorectal carcinogenesis and to inhibit calcium hydroxyapatite precipitation to study the pathogenesis of black pigment gallstones. This product has also been shown to induce apoptosis in isolated hepatocytes via modulation of PKC activity. This compound is used as an anionic detergent to solubilize lipids and as a chiral reagent.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).