Genz-123346
CAY-28500-100 100 mg
Data Sheet: 
SDS:
SDS:
CAS
491833-30-8
Formulation
A crystalline solid
Purity
≥98%
MW
418,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Genz-123346 is a glucosylceramide synthase inhibitor (IC50 = 14 nM).{46474} It reduces hepatic levels of glucosylceramide and triglycerides as well as blood levels of alanine aminotransferase (ALT), hemoglobin A1c, and non-fasting glucose in ob/ob mice when administered at a dose of 120 mg/kg per day.{46475} Genz-123346 (125 mg/kg per day) also decreases hepatic fat mass and reduces the size and number of hepatic lipid droplets in diet-induced obese mice.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
