GLP-1R Agonist DMB
CAY-29678-5 5 mg
Synonyms: Glucagon-like Peptide 1 Receptor Agonist DMB
Data Sheet: 
SDS:
SDS:
CAS
281209-71-0
Formulation
A crystalline solid
Purity
≥98%
MW
348,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
GLP-1R agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).{46660} It inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM.{46661} GLP-1R (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose (Item No. 23733) in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice. It reduces fasting plasma glucose levels in mice when administered at a dose of 5 µmol/kg.{46662}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
